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five–4 μmol/L vary,[156][157] the focus of serotonin in synaptic vesicles was measured at 270 mM.[182] adhering to vesicular release, the resulting focus of serotonin from the synaptic cleft, to which serotonin receptors are exposed, is believed to become about three hundred μmol/L. Hence, even though in vitro receptor binding affinities, eff